ERCC5 Antibody
| Code | Size | Price |
|---|
| PSI-59-501-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
DNA repair protein complementing XP-G cells, 31--, DNA excision repair protein ERCC-5, Xeroderma pigmentosum group G-complementing protein, ERCC5, ERCM2, XPG, XPGC
Application Note:
For WB starting dilution is: 1:1000
Background:
Excision repair cross-complementing rodent repair
deficiency, complementation group 5 (xeroderma pigmentosum,
complementation group G) is involved in excision repair of
UV-induced DNA damage. Mutations cause Cockayne syndrome, which is
characterized by severe growth defects, mental retardation, and
cachexia. Multiple alternatively spliced transcript variants
encoding distinct isoforms have been described, but the biological
validity of all variants has not been determined. [provided by
RefSeq].
Background References:
- Figl, A., et al. Mutat. Res. 702(1):8-16(2010)
- Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :
- Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)
- Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ERCC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1151-1178 amino acids from the C-terminal region of human ERCC5.
NCBI Gene ID #:
2073
NCBI Official Name:
DNA repair protein complementing XP-G cells
NCBI Official Symbol:
ERCC5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
133 kDa
Protein Accession #:
P28715
Protein GI Number:
205371791
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P28715
User NOte:
Optimal dilutions for each application to be determined by the researcher.