PMS1 Antibody
Code | Size | Price |
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PSI-58-143-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
PMS1 protein homolog 1, DNA mismatch repair protein PMS1, PMS1, PMSL1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein belonging to the DNA mismatch
repair mutL/hexB family. This protein is thought to be involved in
the repair of DNA mismatches, and it can form heterodimers with
MLH1, a known DNA mismatch repair protein. Mutations in this gene
cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3)
either alone or in combination with mutations in other genes
involved in the HNPCC phenotype, which is also known as Lynch
syndrome.
Background References:
- Hong, K.W., et al. J. Hum. Genet. 55(6):336-341(2010)
- Monsees, G.M., et al. Breast Cancer Res. Treat. (2010) In press :
- Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)
- Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PMS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 694-722 amino acids from the C-terminal region of human PMS1.
NCBI Gene ID #:
5378
NCBI Official Name:
PMS1 protein homolog 1
NCBI Official Symbol:
PMS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
106 kDa
Protein Accession #:
P54277
Protein GI Number:
1709683
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P54277
User NOte:
Optimal dilutions for each application to be determined by the researcher.