DLX4 Antibody

ProSci
Product Code: PSI-57-441
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-441-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in K562 cell line lysates (35ug/lane).
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Western blot analysis of DLX4 using rabbit polyclonal DLX4 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DLX4 gene.

Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis of DLX4 using rabbit polyclonal DLX4 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DLX4 gene.

Further Information

Additional Names:
Homeobox protein DLX-4, Beta protein 1, Homeobox protein DLX-7, Homeobox protein DLX-8, DLX4, BP1, DLX7, DLX8, DLX9
Application Note:
For WB starting dilution is: 1:1000
Background:
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. Three transcript variants have been described for this gene, however, the full length nature of one variant has not been described. Studies of the two splice variants revealed that one encoded isoform functions as a repressor of the beta-globin gene while the other isoform lacks that function.
Background References:
  • Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
  • Schwartz, A.M., et al. Mod. Pathol. 22(1):1-6(2009)
  • Man, Y.G., et al. Cancer Biomark 5(1):9-17(2009)
  • Cavalli, L.R., et al. Cancer Genet. Cytogenet. 187(1):19-24(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DLX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-100 amino acids from the Central region of human DLX4.
NCBI Gene ID #:
1748
NCBI Official Name:
Homeobox protein DLX-4
NCBI Official Symbol:
DLX4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
Protein Accession #:
Q92988
Protein GI Number:
85700416
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q92988
User NOte:
Optimal dilutions for each application to be determined by the researcher.