GAR1 Antibody
| Code | Size | Price |
|---|
| PSI-60-507-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
H/ACA ribonucleoprotein complex subunit 1, Nucleolar protein family A member 1, snoRNP protein GAR1, GAR1, NOLA1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the H/ACA snoRNPs (small
nucleolar ribonucleoproteins) gene family. snoRNPs are involved in
various aspects of rRNA processing and modification and have been
classified into two families: C/D and H/ACA. The H/ACA snoRNPs also
include the DKC1, NOLA2 and NOLA3 proteins. These four H/ACA snoRNP
proteins localize to the dense fibrillar components of nucleoli and
to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production
and rRNA pseudouridylation are impaired if any one of the four
proteins is depleted. These four H/ACA snoRNP proteins are also
components of the telomerase complex. The encoded protein of this
gene contains two glycine- and arginine-rich domains and is related
to Saccharomyces cerevisiae Gar1p. Two splice variants have been
found for this gene.
Background References:
- Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
- Hamma, T., et al. J. Biol. Chem. 285(2):805-809(2010)
- Pigullo, S., et al. Pediatr Blood Cancer 52(3):376-378(2009)
- Vasan, R.S., et al. BMC Med. Genet.SUPPL 1, S2 (2007) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Zebrafish, Rat
Immunogen:
This GAR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the Central region of human GAR1.
NCBI Gene ID #:
54433
NCBI Official Name:
H/ACA ribonucleoprotein complex subunit 1
NCBI Official Symbol:
GAR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
Q9NY12
Protein GI Number:
51828015
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9NY12
User NOte:
Optimal dilutions for each application to be determined by the researcher.