DUS2L Antibody
| Code | Size | Price |
|---|
| PSI-59-760-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like, 131-, Dihydrouridine synthase 2, Up-regulated in lung cancer protein 8, URLC8, tRNA-dihydrouridine synthase 2-like, hDUS2, DUS2, DUS2L
Application Note:
For WB starting dilution is: 1:1000
Background:
Dihydrouridine synthase catalyzes reduction of the
5,6-double bond of a uridine residue on the displacement loop of
tRNA. The resultant modified base, 5,6-dihydrouridine, appears to
increase the conformational flexibility and dynamic motion of tRNA
(Kato et al., 2005 [PubMed 15994936]).
Background References:
- Mittelstadt, M., et al. Nucleic Acids Res. 36(3):998-1008(2008)
- Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
- Lamesch, P., et al. Genomics 89(3):307-315(2007)
- Kato, T., et al. Cancer Res. 65(13):5638-5646(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DUS2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-397 amino acids from the C-terminal region of human DUS2L.
NCBI Gene ID #:
54920
NCBI Official Name:
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
NCBI Official Symbol:
DUS2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
Q9NX74
Protein GI Number:
73620832
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9NX74
User NOte:
Optimal dilutions for each application to be determined by the researcher.