PVR Antibody
| Code | Size | Price |
|---|
| PSI-60-818-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Poliovirus receptor, Nectin-like protein 5, NECL-5, CD155, PVR, PVS
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a transmembrane
glycoprotein belonging to the immunoglobulin superfamily. The
external domain mediates cell attachment to the extracellular
matrix molecule vitronectin, while its intracellular domain
interacts with the dynein light chain Tctex-1/DYNLT1. The gene is
specific to the primate lineage, and serves as a cellular receptor
for poliovirus in the first step of poliovirus replication.
Multiple transcript variants encoding different isoforms have been
found for this gene.
Background References:
- Nakai, R., et al. Cancer Sci. 101(5):1326-1330(2010)
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
- Stanietsky, N., et al. Proc. Natl. Acad. Sci. U.S.A. 106(42):17858-17863(2009)
- Carlsten, M., et al. J. Immunol. 183(8):4921-4930(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PVR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-342 amino acids from the C-terminal region of human PVR.
NCBI Gene ID #:
5817
NCBI Official Name:
Poliovirus receptor
NCBI Official Symbol:
PVR
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
P15151
Protein GI Number:
1346922
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P15151
User NOte:
Optimal dilutions for each application to be determined by the researcher.