XPA Antibody
| Code | Size | Price |
|---|
| PSI-57-303-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
DNA repair protein complementing XP-A cells, Xeroderma pigmentosum group A-complementing protein, XPA, XPAC
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a zinc finger protein involved in DNA
excision repair. The encoded protein is part of the NER (nucleotide
excision repair) complext which is responsible for repair of UV
radiation-induced photoproducts and DNA adducts induced by chemical
carcinogens. Mutations in this gene are associated with xeroderma
pigmentosum complementation group A. Alternatively spliced
transcript variants have been found for this gene. [provided by
RefSeq].
Background References:
- Palli, D., et al. Mutagenesis 25(6):569-575(2010)
- Fan, W., et al. Mol. Cell 39(2):247-258(2010)
- Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :
- Hsieh, Y.Y., et al. Anticancer Res. 30(6):2203-2208(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This XPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-213 amino acids from the C-terminal region of human XPA.
NCBI Gene ID #:
7507
NCBI Official Name:
DNA repair protein complementing XP-A cells
NCBI Official Symbol:
XPA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
31 kDa
Protein Accession #:
P23025
Protein GI Number:
139816
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P23025
User NOte:
Optimal dilutions for each application to be determined by the researcher.