RPN1 Antibody
Code | Size | Price |
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PSI-58-863-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit, Ribophorin I, RPN-I, Ribophorin-1, RPN1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a type I integral membrane protein found
only in the rough endoplasmic reticulum. The encoded protein is
part of an N-oligosaccharyl transferase complex that links high
mannose oligosaccharides to asparagine residues found in the
Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This
protein forms part of the regulatory subunit of the 26S proteasome
and may mediate binding of ubiquitin-like domains to this
proteasome.
Background References:
- Ruiz-Canada, C., et al. Cell 136(2):272-283(2009)
- Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)
- Wilson, C.M., et al. Proc. Natl. Acad. Sci. U.S.A. 105(28):9534-9539(2008)
- Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Pig, Rat
Immunogen:
This RPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 559-587 amino acids from the C-terminal region of human RPN1.
NCBI Gene ID #:
6184
NCBI Official Name:
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1
NCBI Official Symbol:
RPN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
69 kDa
Protein Accession #:
P04843
Protein GI Number:
132559
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P04843
User NOte:
Optimal dilutions for each application to be determined by the researcher.