CTSZ Antibody

ProSci
Product Code: PSI-55-642
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-55-642-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in T47D cell line lysates (35ug/lane).

Western blot analysis in T47D cell line lysates (35ug/lane).

Further Information

Additional Names:
Cathepsin Z, Cathepsin P, Cathepsin X, CTSZ
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis.
Background References:
  • Starr, J.M., et al. Mech. Ageing Dev. 129(12):745-751(2008)
  • Cooke, G.S., et al. Am. J. Respir. Crit. Care Med. 178(2):203-207(2008)
  • Harris, S.E., et al. BMC Genet. 8, 43 (2007) :
  • Lechner, A.M., et al. J. Biol. Chem. 281(51):39588-39597(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CTSZ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-50 amino acids from the N-terminal region of human CTSZ.
NCBI Gene ID #:
1522
NCBI Official Name:
Cathepsin Z
NCBI Official Symbol:
CTSZ
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
34 kDa
Protein Accession #:
Q9UBR2
Protein GI Number:
12643324
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9UBR2
User NOte:
Optimal dilutions for each application to be determined by the researcher.