HNRNPH1 Antibody

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ProSci
Product Code: PSI-60-849
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-60-849-400ul400ul£626.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

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Further Information

Additional Names:
Heterogeneous nuclear ribonucleoprotein H, hnRNP H, Heterogeneous nuclear ribonucleoprotein H, N-terminally processed, HNRNPH1, HNRPH, HNRPH1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. It is very similar to the family member HNRPF. This gene is thought to be potentially involved in hereditary lymphedema type I phenotype. [provided by RefSeq].
Background References:
  • Van Dusen, C.M., et al. Mol. Cell. Biol. 30(10):2552-2562(2010)
  • Russo, A., et al. Biochim. Biophys. Acta 1799 (5-6), 419-428 (2010) :
  • Ohe, K., et al. J. Biochem. 147(5):651-659(2010)
  • Rauch, J., et al. Cancer Res. 70(4):1679-1688(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat, Bovine
Immunogen:
This HNRNPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human HNRNPH1.
NCBI Gene ID #:
3187
NCBI Official Name:
Heterogeneous nuclear ribonucleoprotein H
NCBI Official Symbol:
HNRNPH1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa
Protein Accession #:
P31943
Protein GI Number:
1710632
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P31943
User NOte:
Optimal dilutions for each application to be determined by the researcher.