HNRPDL Antibody

ProSci
Product Code: PSI-61-897
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-897-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in K562,HepG2,Jurkat cell line lysates (35ug/lane).

Western blot analysis in K562,HepG2,Jurkat cell line lysates (35ug/lane).

Further Information

Additional Names:
Heterogeneous nuclear ribonucleoprotein D-like, hnRNP D-like, hnRNP DL, AU-rich element RNA-binding factor, JKT41-binding protein, Protein laAUF1, HNRNPDL, HNRPDL, JKTBP
Application Note:
For WB starting dilution is: 1:1000
Background:
HNRPDL belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein has two RRM domains that bind to RNAs.
Background References:
  • Walker, L.C., et al. Breast Cancer Res. Treat. 112(2):229-236(2008)
  • Wu, Y.Y., et al. Cell Biochem. Funct. 26(4):467-477(2008)
  • Reboll, M.R., et al. RNA 13(8):1328-1340(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Xenopus, Chicken, Mouse, Rat
Immunogen:
This HNRPDL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the Central region of human HNRPDL.
NCBI Gene ID #:
9987
NCBI Official Name:
Heterogeneous nuclear ribonucleoprotein D-like
NCBI Official Symbol:
HNRNPDL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Protein Accession #:
O14979
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O14979
User NOte:
Optimal dilutions for each application to be determined by the researcher.