MCPH1 Antibody
| Code | Size | Price |
|---|
| PSI-57-564-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Microcephalin, MCPH1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a DNA damage response protein. The
encoded protein may play a role in G2/M checkpoint arrest via
maintenance of inhibitory phosphorylation of cyclin-dependent
kinase 1. Mutations in this gene have been associated with primary
autosomal recessive microcephaly 1 and premature chromosome
condensation syndrome. Alternatively spliced transcript variants
have been described.
Background References:
- Wang, Y., et al. J. Hum. Genet. 55(8):490-494(2010)
- Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This MCPH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human MCPH1.
NCBI Gene ID #:
79648
NCBI Official Name:
Microcephalin
NCBI Official Symbol:
MCPH1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
93 kDa
Protein Accession #:
Q8NEM0
Protein GI Number:
296439305
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q8NEM0
User NOte:
Optimal dilutions for each application to be determined by the researcher.