MTIF2 Antibody

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ProSci
Product Code: PSI-58-834
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-834-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

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Western blot analysis of lysate from SK-BR-3 cell line, using MTIF2 Antibody at 1:1000 at each lane.
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Western blot analysis of lysate from SK-BR-3 cell line, using MTIF2 Antibody at 1:1000 at each lane.

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Further Information

Additional Names:
Translation initiation factor IF-2, mitochondrial, IF-2(Mt), IF-2Mt, IF2(mt), MTIF2
Application Note:
For WB starting dilution is: 1:1000
Background:
During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38% amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
Background References:
  • Dick, D.M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. (2010) In press :
  • Reiling, E., et al. Eur. J. Hum. Genet. 17(8):1056-1062(2009)
  • Miura, E., et al. Plant Cell 19(4):1313-1328(2007)
  • Bouwmeester, T., et al. Nat. Cell Biol. 6(2):97-105(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MTIF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-167 amino acids from the N-terminal region of human MTIF2.
NCBI Gene ID #:
4528
NCBI Official Name:
Translation initiation factor IF-2, mitochondrial
NCBI Official Symbol:
MTIF2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
81 kDa
Protein Accession #:
P46199
Protein GI Number:
223590069
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P46199
User NOte:
Optimal dilutions for each application to be determined by the researcher.