EIF2B3 Antibody
| Code | Size | Price |
|---|
| PSI-58-888-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Translation initiation factor eIF-2B subunit gamma, eIF-2B GDP-GTP exchange factor subunit gamma, EIF2B3
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is one of the subunits of
initiation factor eIF2B, which catalyzes the exchange of eukaryotic
initiation factor 2-bound GDP for GTP. It has also been found to
function as a cofactor of hepatitis C virus internal ribosome entry
site-mediated translation. Mutations in this gene have been
associated with leukodystrophy with vanishing white matter.
Alternatively spliced transcript variants encoding different
isoforms have been found for this gene.
Background References:
- Rose, J. Phd, et al. Mol. Med. (2010) In press :
- Pronk, J., et al. Mult. Scler. 14(8):1123-1126(2008)
- Maletkovic, J., et al. J. Child Neurol. 23(2):205-215(2008)
- Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This EIF2B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 413-441 amino acids from the C-terminal region of human EIF2B3.
NCBI Gene ID #:
8891
NCBI Official Name:
Translation initiation factor eIF-2B subunit gamma
NCBI Official Symbol:
EIF2B3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
Q9NR50
Protein GI Number:
18203317
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9NR50
User NOte:
Optimal dilutions for each application to be determined by the researcher.