PTRH1 Antibody

ProSci
Product Code: PSI-59-426
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-426-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

Further Information

Additional Names:
Probable peptidyl-tRNA hydrolase, PTH, PTRH1, C9orf115
Application Note:
For WB starting dilution is: 1:1000
Background:
C9orf115 belongs to the Peptidyl-tRNA hydrolase (PTH) family. Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through abortion of translation and is essential for cell viability.
Background References:
  • Satoh, J., et al. Neuropathol. Appl. Neurobiol. 35(1):16-35(2009)
  • De Pereda, J.M., et al. J. Biol. Chem. 279(9):8111-8115(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PTRH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-129 amino acids from the Central region of human PTRH1.
NCBI Gene ID #:
138428
NCBI Official Name:
Probable peptidyl-tRNA hydrolase
NCBI Official Symbol:
PTRH1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
23 kDa
Protein Accession #:
Q86Y79
Protein GI Number:
74750555
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q86Y79
User NOte:
Optimal dilutions for each application to be determined by the researcher.