RBM28 Antibody

ProSci
Product Code: PSI-56-668
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-668-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MCF-7 cell line lysates (35ug/lane).

Western blot analysis in MCF-7 cell line lysates (35ug/lane).

Further Information

Additional Names:
RNA-binding protein 28, RNA-binding motif protein 28, RBM28
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a specific nucleolar component of the spliceosomal small nuclear ribonucleoprotein (snRNP)complexes . It specifically associates with U1, U2, U4, U5, and U6 small nuclear RNAs (snRNAs), possibly coordinating their transition through the nucleolus. Mutation in this gene causes alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome), a pleiotropic and clinically heterogeneous disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Spiegel, R., et al. Eur. J. Endocrinol. 162(6):1021-1025(2010)
  • Nousbeck, J., et al. Am. J. Hum. Genet. 82(5):1114-1121(2008)
  • Damianov, A., et al. Biol. Chem. 387 (10-11), 1455-1460 (2006) :
  • Andersen, J.S., et al. Nature 433(7021):77-83(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RBM28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-91 amino acids from the N-terminal region of human RBM28.
NCBI Gene ID #:
55131
NCBI Official Name:
RNA-binding protein 28
NCBI Official Symbol:
RBM28
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
86 kDa
Protein Accession #:
Q9NW13
Protein GI Number:
55976611
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9NW13
User NOte:
Optimal dilutions for each application to be determined by the researcher.