FARP1 Antibody

ProSci
Product Code: PSI-59-589
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-589-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A375 cell line lysates (35ug/lane).

Western blot analysis in A375 cell line lysates (35ug/lane).

Further Information

Additional Names:
FERM, RhoGEF and pleckstrin domain-containing protein 1, Chondrocyte-derived ezrin-like protein, Pleckstrin homology domain-containing family C member 2, PH domain-containing family C member 2, FARP1, CDEP, PLEKHC2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene was originally isolated through subtractive hybridization due to its increased expression in differentiated chondrocytes versus dedifferentiated chondrocytes. The resulting protein contains a predicted ezrin-like domain, a Dbl homology domain, and a pleckstrin homology domain. It is believed to be a member of the band 4.1 superfamily whose members link the cytoskeleton to the cell membrane. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Background References:
  • Stein, J.L., et al. Neuroimage 53(3):1160-1174(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Evangelou, E., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (1), 220-228 (2010) :
  • Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken
Immunogen:
This FARP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-90 amino acids from the N-terminal region of human FARP1.
NCBI Gene ID #:
10160
NCBI Official Name:
FERM, RhoGEF and pleckstrin domain-containing protein 1
NCBI Official Symbol:
FARP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
119 kDa
Protein Accession #:
Q9Y4F1
Protein GI Number:
74762059
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9Y4F1
User NOte:
Optimal dilutions for each application to be determined by the researcher.