ZNF384 Antibody

ProSci
Product Code: PSI-56-131
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-131-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MCF-7,Hela cell line lysates (35ug/lane).
2 / 2
Flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Western blot analysis in MCF-7,Hela cell line lysates (35ug/lane).
Flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Further Information

Additional Names:
Zinc finger protein 384, CAG repeat protein 1, CAS-interacting zinc finger protein, Nuclear matrix transcription factor 4, Nuclear matrix protein 4, Trinucleotide repeat-containing gene 1 protein, ZNF384, CAGH1, CIZ, NMP4, TNRC1
Application Note:
For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50
Background:
This gene contains long CAG trinucleotide repeats coding consecutive glutamine residues. The gene product may functions as a transcription factor, with a potential role in the regulation of neurodevelopment or neuroplasticity. The protein appears to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Multiple transcript variants encoding several isoforms have been found for this gene.
Background References:
  • Alves, J., et al. Biochem. Biophys. Res. Commun. 384(4):495-500(2009)
  • Zhong, C.H., et al. Leukemia 22(4):723-729(2008)
  • Janssen, H., et al. Exp. Cell Res. 312(7):1194-1204(2006)
  • La Starza, R., et al. Leukemia 19(9):1696-1699(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ZNF384 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-559 amino acids from the C-terminal region of human ZNF384.
NCBI Gene ID #:
171017
NCBI Official Name:
Zinc finger protein 384
NCBI Official Symbol:
ZNF384
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
63 kDa
Protein Accession #:
Q8TF68
Protein GI Number:
296453052
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q8TF68
User NOte:
Optimal dilutions for each application to be determined by the researcher.