RNASEH2B Antibody
| Code | Size | Price |
|---|
| PSI-61-658-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Ribonuclease H2 subunit B, RNase H2 subunit B, Aicardi-Goutieres syndrome 2 protein, AGS2, Deleted in lymphocytic leukemia 8, Ribonuclease HI subunit B, RNASEH2B, DLEU8
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
RNASEH2B is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. RNASEH2B is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication.
Background References:
- Crozat, K., et al. Immunol. Rev. 227(1):129-149(2009)
- Chon, H., et al. Nucleic Acids Res. 37(1):96-110(2009)
- Crow, Y.J., et al. Dev Med Child Neurol 50(6):410-416(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RNASEH2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-157 amino acids from the Central region of human RNASEH2B.
NCBI Gene ID #:
79621
NCBI Official Name:
Ribonuclease H2 subunit B
NCBI Official Symbol:
RNASEH2B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
35 kDa
Protein Accession #:
Q5TBB1
Protein GI Number:
74745929
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q5TBB1
User NOte:
Optimal dilutions for each application to be determined by the researcher.