PURA Antibody
| Code | Size | Price |
|---|
| PSI-56-040-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Transcriptional activator protein Pur-alpha, Purine-rich single-stranded DNA-binding protein alpha, PURA, PUR1
Application Note:
For IHC-P starting dilution is: 1:50~100
For WB starting dilution is: 1:1000
For WB starting dilution is: 1:1000
Background:
This gene product is a sequence-specific, single-stranded
DNA-binding protein. It binds preferentially to the single strand
of the purine-rich element termed PUR, which is present at origins
of replication and in gene flanking regions in a variety of
eukaryotes from yeasts through humans. Thus, it is implicated in
the control of both DNA replication and transcription. Deletion of
this gene has been associated with myelodysplastic syndrome and
acute myelogenous leukemia.
Background References:
- Inoue, T., et al. Prostate 69(8):861-873(2009)
- Martins-de-Souza, D., et al. Eur Arch Psychiatry Clin Neurosci 259(3):151-163(2009)
- Kaminski, R., et al. Cancer Biol. Ther. 7(12):1926-1935(2008)
- Darbinian, N., et al. J. Alzheimers Dis. 15(1):71-82(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This PURA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the C-terminal region of human PURA.
NCBI Gene ID #:
5813
NCBI Official Name:
Transcriptional activator protein Pur-alpha
NCBI Official Symbol:
PURA
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
35 kDa
Protein Accession #:
Q00577
Protein GI Number:
1346918
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q00577
User NOte:
Optimal dilutions for each application to be determined by the researcher.