CYP4X1 Antibody

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ProSci
Product Code: PSI-63-268
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-63-268-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of anti-CYP4X1 Antibody in T47D cell line lysates (35ug/lane)
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Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CYP4X1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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Western blot analysis of anti-CYP4X1 Antibody in T47D cell line lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CYP4X1 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Documents

Further Information

Additional Names:
Cytochrome P450 4X1, CYPIVX1, CYP4X1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
CYP4X1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain.
Background References:
  • Savas,U., Arch. Biochem. Biophys. 436 (2), 377-385 (2005)
  • Nelson,D.R., Pharmacogenetics 14 (1), 1-18 (2004)
  • Bylund,J., Biochem. Biophys. Res. Commun. 296 (3), 677-684 (2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CYP4X1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-183 amino acids from the N-terminal region of human CYP4X1.
NCBI Gene ID #:
260293
NCBI Official Name:
Cytochrome P450 4X1
NCBI Official Symbol:
CYP4X1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
Q8N118
Protein GI Number:
48428082
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Swissprot #:
Q8N118
User NOte:
Optimal dilutions for each application to be determined by the researcher.