RIC3 Antibody

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ProSci
Product Code: PSI-56-602
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-602-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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RIC3 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis in NCI-H292,A549,WiDr,MDA-MB453 cell line lysates (35ug/lane).
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RIC3 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in NCI-H292,A549,WiDr,MDA-MB453 cell line lysates (35ug/lane).

Documents

Further Information

Additional Names:
Protein RIC-3, Resistant to inhibitor of cholinesterase 3, RIC3
Application Note:
For IHC-P starting dilution is: 1:10~50

For WB starting dilution is: 1:1000
Background:
RIC3 is a protein associated with nicotinic acetylcholine receptors (nAChRs), neurotransmitter-gated ion channels expressed at the neuromuscular junction and within the central and peripheral nervous systems, that can enhance functional expression of multiple nAChR subtypes (Lansdell et al., 2005 [PubMed 16120769]).[supplied by OMIM].
Background References:
  • Walstab, J., et al. J. Biol. Chem. 285(35):26956-26965(2010)
  • Bailey, S.D., et al. Diabetes Care (2010) In press :
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
  • Seredenina, T., et al. Biosci. Rep. 28(6):299-306(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RIC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-341 amino acids from the C-terminal region of human RIC3.
NCBI Gene ID #:
79608
NCBI Official Name:
Protein RIC-3
NCBI Official Symbol:
RIC3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
Q7Z5B4
Protein GI Number:
74713638
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q7Z5B4
User NOte:
Optimal dilutions for each application to be determined by the researcher.