KCNH7 Antibody

ProSci
Product Code: PSI-63-817
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-817-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of KCNH7 Antibody in T47D cell line lysates (35ug/lane)
2 / 3
Formalin-fixed and paraffin-embedded human brain tissue reacted with KCNH7 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
3 / 3

Western blot analysis of KCNH7 Antibody in T47D cell line lysates (35ug/lane)
Formalin-fixed and paraffin-embedded human brain tissue reacted with KCNH7 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Further Information

Additional Names:
Potassium voltage-gated channel subfamily H member 7, Ether-a-go-go-related gene potassium channel 3, ERG-3, Eag-related protein 3, Ether-a-go-go-related protein 3, hERG-3, Voltage-gated potassium channel subunit Kv113, KCNH7, ERG3
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50
Background:
KCNH7 represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This protein encodes a member of the potassium channel, voltage-gated, subfamily H.
Background References:
  • Alkelai,A., et.al., Psychopharmacology (Berl.) 206 (3), 491-499 (2009)
  • Couturier,N., et.al., Eur. J. Hum. Genet. 17 (6), 844-847 (2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This KCNH7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-78 amino acids from the N-terminal region of human KCNH7.
NCBI Gene ID #:
90134
NCBI Official Name:
Potassium voltage-gated channel subfamily H member 7
NCBI Official Symbol:
KCNH7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
135 kDa
Protein Accession #:
Q9NS40
Protein GI Number:
229462892
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9NS40
User NOte:
Optimal dilutions for each application to be determined by the researcher.