DOC2A Antibody
| Code | Size | Price |
|---|
| PSI-56-685-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Double C2-like domain-containing protein alpha, Doc2, Doc2-alpha, DOC2A
Application Note:
For FACS starting dilution is: 1:10~50
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Background:
There are at least two protein isoforms of the Double C2
protein, namely alpha (DOC2A) and beta (DOC2B), which contain two
C2-like domains. DOC2A and DOC2B are encoded by different genes;
these genes are at times confused with the unrelated DAB2 gene
which was initially named DOC-2. DOC2A is mainly expressed in brain
and is suggested to be involved in Ca(2+)-dependent
neurotransmitter release.
Background References:
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Glessner, J.T., et al. Proc. Natl. Acad. Sci. U.S.A. 107(23):10584-10589(2010)
- Guilmatre, A., et al. Arch. Gen. Psychiatry 66(9):947-956(2009)
- Kumar, R.A., et al. PLoS ONE(2), E4582 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This DOC2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the Central region of human DOC2A.
NCBI Gene ID #:
8448
NCBI Official Name:
Double C2-like domain-containing protein alpha
NCBI Official Symbol:
DOC2A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
Q14183
Protein GI Number:
150421541
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q14183
User NOte:
Optimal dilutions for each application to be determined by the researcher.