FOLR1 Antibody
| Code | Size | Price |
|---|
| PSI-55-347-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Folate receptor alpha, FR-alpha, Adult folate-binding protein, FBP, Folate receptor 1, Folate receptor, adult, KB cells FBP, Ovarian tumor-associated antigen MOv18, FOLR1, FOLR
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a member of the folate
receptor family. Members of this gene family bind folic acid and
its reduced derivatives, and transport 5-methyltetrahydrofolate
into cells. This gene product is a secreted protein that either
anchors to membranes via a glycosyl-phosphatidylinositol linkage or
exists in a soluble form. Mutations in this gene have been
associated with neurodegeneration due to cerebral folate transport
deficiency. Due to the presence of two promoters, multiple
transcription start sites, and alternative splicing, multiple
transcript variants encoding the same protein have been found for
this gene.
Background References:
- Sivakumaran, S., et al. J. Steroid Biochem. Mol. Biol. 122(5):333-340(2010)
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- O'Byrne, M.R., et al. Birth Defects Res. PartClin. Mol. Teratol. 88(8):689-694(2010)
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FOLR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-68 amino acids from the N-terminal region of human FOLR1.
NCBI Gene ID #:
2348
NCBI Official Name:
Folate receptor alpha
NCBI Official Symbol:
FOLR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
30 kDa
Protein Accession #:
P15328
Protein GI Number:
544337
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P15328
User NOte:
Optimal dilutions for each application to be determined by the researcher.