NM23 Antibody
Code | Size | Price |
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PSI-63-384-400ul | 400ul | £626.00 |
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Nucleoside diphosphate kinase A, NDK A, NDP kinase A, Granzyme A-activated DNase, GAAD, Metastasis inhibition factor nm23, NM23-H1, Tumor metastatic process-associated protein, NME1, NDPKA, NM23
Application Note:
For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100
For IF starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100
Background:
NME1 was identified because of its reduced mRNA transcript levels in highly metastatic cells. NME1 encodes the 'A' isoform of nucleoside diphosphate kinase (NDK). NDK exists as a hexamer composed of the 'A' (NME1) and 'B' (encoded by NME2) isoforms. Mutations in NME1 have been identified in aggressive neuroblastomas.
Background References:
- Munier, A., et al., Exp. Cell Res. 289(2):295-306 (2003).
- Chen, Y., et al., J. Mol. Biol. 332(4):915-926 (2003).
- Kim, Y.I., et al., Biochem. Biophys. Res. Commun. 307(2):281-289 (2003).
- Wang, P.H., et al., Gynecol. Obstet. Invest. 55(1):14-19 (2003).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NM23 (NME1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human NM23 (NME1).
NCBI Gene ID #:
4830
NCBI Official Name:
Nucleoside diphosphate kinase A
NCBI Official Symbol:
NME1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
17 kDa
Protein Accession #:
P15531
Protein GI Number:
127981
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P15531
User NOte:
Optimal dilutions for each application to be determined by the researcher.