EXOSC1 Antibody

Contact us
ProSci
Product Code: PSI-59-892
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-892-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 1
Western blot analysis in 293 cell line lysates (35ug/lane).
❮❯

Western blot analysis in 293 cell line lysates (35ug/lane).

Documents

Further Information

Additional Names:
Exosome complex component CSL4, Exosome component 1, EXOSC1, CSL4
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46.
Background References:
  • Andersen, J.S., et al. Nature 433(7021):77-83(2005)
  • Lehner, B., et al. Genome Res. 14(7):1315-1323(2004)
  • Deloukas, P., et al. Nature 429(6990):375-381(2004)
  • Raijmakers, R., et al. J. Mol. Biol. 323(4):653-663(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This EXOSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-191 amino acids from the C-terminal region of human EXOSC1.
NCBI Gene ID #:
51013
NCBI Official Name:
Exosome complex component CSL4
NCBI Official Symbol:
EXOSC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
Q9Y3B2
Protein GI Number:
14285410
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9Y3B2
User NOte:
Optimal dilutions for each application to be determined by the researcher.