MTRF1 Antibody
Code | Size | Price |
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PSI-59-226-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Peptide chain release factor 1, mitochondrial, MRF-1, MtRF-1, MTRF1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene was determined by in
silico methods to be a mitochondrial protein with similarity to the
peptide chain release factors (RFs) discovered in bacteria and
yeast. The peptide chain release factors direct the termination of
translation in response to the peptide chain termination codons.
Initially thought to have a role in the termination of mitochondria
protein synthesis, a recent publication found no mitochondrial
translation release functionality. Multiple alternatively spliced
transcript variants have been suggested by mRNA and EST data;
however, their full-length natures are not clear. [provided by
RefSeq].
Background References:
- Antonicka, H., et al. Am. J. Hum. Genet. 87(1):115-122(2010)
- Nozaki, Y., et al. Genes Cells 13(5):429-438(2008)
- Soleimanpour-Lichaei, H.R., et al. Mol. Cell 27(5):745-757(2007)
- Hansen, L.L., et al. Cytogenet. Cell Genet. 88 (1-2), 91-92 (2000) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This MTRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-259 amino acids from the Central region of human MTRF1.
NCBI Gene ID #:
9617
NCBI Official Name:
Peptide chain release factor 1, mitochondrial
NCBI Official Symbol:
MTRF1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
O75570
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O75570
User NOte:
Optimal dilutions for each application to be determined by the researcher.