CELA2A Antibody

ProSci
Product Code: PSI-57-413
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-413-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution + human pancreas lysate Lysates/proteins at 20 ug per lane.
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Western Blot at 1:1000 dilution + human pancreas lysate Lysates/proteins at 20 ug per lane.
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Western Blot at 1:1000 dilution + human pancreas lysate Lysates/proteins at 20 ug per lane.
Western Blot at 1:1000 dilution + human pancreas lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
Chymotrypsin-like elastase family member 2A, Elastase-2A, CELA2A, ELA2A
Application Note:
For WB starting dilution is: 1:1000
Background:
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues.
Background References:
  • Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
  • Lausen, J., et al. Oncogene 25(9):1349-1357(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Pig
Immunogen:
This CELA2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 231-260 amino acids from the C-terminal region of human CELA2A.
NCBI Gene ID #:
63036
NCBI Official Name:
Chymotrypsin-like elastase family member 2A
NCBI Official Symbol:
CELA2A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
29 kDa
Protein Accession #:
P08217
Protein GI Number:
119255
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P08217
User NOte:
Optimal dilutions for each application to be determined by the researcher.