GEMIN8 Antibody

ProSci
Product Code: PSI-59-561
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-561-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A549 cell line lysates (35ug/lane).

Western blot analysis in A549 cell line lysates (35ug/lane).

Further Information

Additional Names:
Gem-associated protein 8, Gemin-8, Protein FAM51A1, GEMIN8, FAM51A1
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
Background References:
  • Carissimi, C., et al. J. Biol. Chem. 281(48):37009-37016(2006)
  • Carissimi, C., et al. J. Biol. Chem. 281(12):8126-8134(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This GEMIN8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 213-239 amino acids from the C-terminal region of human GEMIN8.
NCBI Gene ID #:
54960
NCBI Official Name:
Gem-associated protein 8
NCBI Official Symbol:
GEMIN8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
29 kDa
Protein Accession #:
Q9NWZ8
Protein GI Number:
52782795
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9NWZ8
User NOte:
Optimal dilutions for each application to be determined by the researcher.