EME2 Antibody

ProSci
Product Code: PSI-58-422
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-422-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

Further Information

Additional Names:
Probable crossover junction endonuclease EME2, 3122-, EME2
Application Note:
For WB starting dilution is: 1:1000
Background:
EME2 forms a heterodimer with MUS81 (MIM 606591) that functions as an XPF (MIM 278760)-type flap/fork endonuclease in DNA repair (Ciccia et al., 2007 [PubMed 17289582]).
Background References:
  • Ciccia, A., et al. Mol. Cell 25(3):331-343(2007)
  • Ciccia, A., et al. J. Biol. Chem. 278(27):25172-25178(2003)
  • Daniels, R.J., et al. Hum. Mol. Genet. 10(4):339-352(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This EME2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-278 amino acids from the C-terminal region of human EME2.
NCBI Gene ID #:
197342
NCBI Official Name:
Probable crossover junction endonuclease EME2
NCBI Official Symbol:
EME2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
A4GXA9
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
A4GXA9
User NOte:
Optimal dilutions for each application to be determined by the researcher.