RNASE1 Antibody
| Code | Size | Price |
|---|
| PSI-60-936-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Ribonuclease pancreatic, HP-RNase, RIB-1, RNase UpI-1, Ribonuclease 1, RNase 1, Ribonuclease A, RNase A, RNASE1, RIB1, RNS1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the pancreatic-type of
secretory ribonucleases, a subset of the ribonuclease A
superfamily. The encoded endonuclease cleaves internal
phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It
prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic
nucleotides, with a pH optimum near 8.0. The encoded protein is
monomeric and more commonly acts to degrade ds-RNA over ss-RNA.
Alternative splicing occurs at this locus and four transcript
variants encoding the same protein have been identified. [provided
by RefSeq].
Background References:
- D'Alessio, G. Biopolymers 91(12):989-994(2009)
- Kover, K.E., et al. J. Mol. Biol. 379(5):953-965(2008)
- Ueki, M., et al. Biochem. Genet. 46 (3-4), 145-153 (2008) :
- Johnson, R.J., et al. Biochemistry 46(36):10308-10316(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RNASE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human RNASE1.
NCBI Gene ID #:
6035
NCBI Official Name:
Ribonuclease pancreatic
NCBI Official Symbol:
RNASE1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
18 kDa
Protein Accession #:
P07998
Protein GI Number:
1350818
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P07998
User NOte:
Optimal dilutions for each application to be determined by the researcher.