SIGLEC10 Antibody

ProSci
Product Code: PSI-59-091
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-091-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MCF-7 cell line lysates (35ug/lane).

Western blot analysis in MCF-7 cell line lysates (35ug/lane).

Further Information

Additional Names:
Sialic acid-binding Ig-like lectin 10, Siglec-10, Siglec-like protein 2, SIGLEC10, SLG2
Application Note:
For WB starting dilution is: 1:1000
Background:
SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. SIGLECs are typically expressed on cells of the innate immune system, with the exception of the B-cell expressed SIGLEC6 (MIM 604405).
Background References:
  • Davila, S., et al. Genes Immun. 11(3):232-238(2010)
  • Kivi, E., et al. Blood 114(26):5385-5392(2009)
  • Szafranski, K., et al. Genome Biol.(8), R154 (2007) :
  • Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SIGLEC10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 667-695 amino acids from the C-terminal region of human SIGLEC10.
NCBI Gene ID #:
89790
NCBI Official Name:
Sialic acid-binding Ig-like lectin 10
NCBI Official Symbol:
SIGLEC10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
77 kDa
Protein Accession #:
Q96LC7
Protein GI Number:
118572721
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q96LC7
User NOte:
Optimal dilutions for each application to be determined by the researcher.