MMRN1 Antibody

ProSci
Product Code: PSI-58-935
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-935-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysates from HLVEC, HUVEC cell line (from left to right), using MMRN1 Antibody at 1:1000 at each lane.

Western blot analysis of lysates from HLVEC, HUVEC cell line (from left to right), using MMRN1 Antibody at 1:1000 at each lane.

Further Information

Additional Names:
Multimerin-1, EMILIN-4, Elastin microfibril interface located protein 4, Elastin microfibril interfacer 4, Endothelial cell multimerin, Platelet glycoprotein Ia*, 155 kDa platelet multimerin, p-155, p155, MMRN1, ECM, EMILIN4, GPIA*, MMRN
Application Note:
For WB starting dilution is: 1:1000
Background:
Multimerin is a massive, soluble protein found in platelets and in the endothelium of blood vessels. It is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. Multimerin is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. It may also have functions as an extracellular matrix or adhesive protein. Recently, patients with an unusual autosomal-dominant bleeding disorder (factor V Quebec) were found to have a deficiency of platelet multimerin.
Background References:
  • Davila, S., et al. Genes Immun. 11(3):232-238(2010)
  • Simon-Sanchez, J., et al. Nat. Genet. 41(12):1308-1312(2009)
  • Tasneem, S., et al. J. Thromb. Haemost. 7(4):685-692(2009)
  • Jeimy, S.B., et al. Thromb. Haemost. 100(6):1058-1067(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MMRN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-207 amino acids from the N-terminal region of human MMRN1.
NCBI Gene ID #:
22915
NCBI Official Name:
Multimerin-1
NCBI Official Symbol:
MMRN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
138 kDa
Protein Accession #:
Q13201
Protein GI Number:
143811421
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q13201
User NOte:
Optimal dilutions for each application to be determined by the researcher.