SF3B4 Antibody
| Code | Size | Price |
|---|
| PSI-60-518-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Splicing factor 3B subunit 4, Pre-mRNA-splicing factor SF3b 49 kDa subunit, SF3b50, Spliceosome-associated protein 49, SAP 49, SF3B4, SAP49
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes one of four subunits of the splicing
factor 3B. The protein encoded by this gene cross-links to a region
in the pre-mRNA immediately upstream of the branchpoint sequence in
pre-mRNA in the prespliceosomal complex A. It also may be involved
in the assembly of the B, C and E spliceosomal complexes. In
addition to RNA-binding activity, this protein interacts directly
and highly specifically with subunit 2 of the splicing factor 3B.
This protein contains two N-terminal RNA-recognition motifs (RRMs),
consistent with the observation that it binds directly to pre-mRNA.
Background References:
- Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
- Rikova, K., et al. Cell 131(6):1190-1203(2007)
- Watanabe, H., et al. J. Biol. Chem. 282(28):20728-20738(2007)
- Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This SF3B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-187 amino acids from the Central region of human SF3B4.
NCBI Gene ID #:
10262
NCBI Official Name:
Splicing factor 3B subunit 4
NCBI Official Symbol:
SF3B4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
Q15427
Protein GI Number:
2500587
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q15427
User NOte:
Optimal dilutions for each application to be determined by the researcher.