F7 Antibody
| Code | Size | Price |
|---|
| PSI-61-240-200ul | 200ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Coagulation factor VII, 3.4.21.21, Proconvertin, Serum prothrombin conversion accelerator, SPCA, Eptacog alfa, Factor VII light chain, Factor VII heavy chain, F7
Application Note:
For WB starting dilution is: 1:2000
Background:
Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
Background References:
- Hagen F.S.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:2412-2416(1986).
- O'Hara P.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:5158-5162(1987).
- Sabater-Lleal M.,et al.Hum. Genet. 118:741-751(2006).
- Soria J.M.,et al.Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This F7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 302-332 amino acids from human F7.
NCBI Gene ID #:
2155
NCBI Official Name:
Coagulation factor VII
NCBI Official Symbol:
F7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
P08709
Protein GI Number:
119766
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P08709
User NOte:
Optimal dilutions for each application to be determined by the researcher.