CSTF3 Antibody

ProSci
Product Code: PSI-57-449
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-449-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

Further Information

Additional Names:
Cleavage stimulation factor subunit 3, CF-1 77 kDa subunit, Cleavage stimulation factor 77 kDa subunit, CSTF 77 kDa subunit, CstF-77, CSTF3
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is one of three (including CSTF1 and CSTF2) cleavage stimulation factors that combine to form the cleavage stimulation factor complex (CSTF). This complex is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex. Alternative splicing results in multiple transcript variants encoding different isoforms.
Background References:
  • Hockert, J.A., et al. J. Biol. Chem. 285(1):695-704(2010)
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
  • Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
  • Olsen, J.V., et al. Cell 127(3):635-648(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This CSTF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 556-585 amino acids from the C-terminal region of human CSTF3.
NCBI Gene ID #:
1479
NCBI Official Name:
Cleavage stimulation factor subunit 3
NCBI Official Symbol:
CSTF3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
83 kDa
Protein Accession #:
Q12996
Protein GI Number:
71153231
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q12996
User NOte:
Optimal dilutions for each application to be determined by the researcher.