SLCO1B3 Antibody

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ProSci
Product Code: PSI-60-227
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-227-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:2000 dilution Lane 1: NCI-H460 whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 ug per lane.
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Western Blot at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: SW480 whole cell lysate Lysates/proteins at 20 ug per lane.
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Western Blot at 1:2000 dilution Lane 1: Hela whole cell lysates Lane 2: PC-3 whole cell lysates Lane 3: SW480 whole cell lysates Lysates/proteins at 20 ug per lane.
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Western Blot at 1:1000 dilution + NCI-H460 whole cell lysates Lysates/proteins at 20 ug per lane.
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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
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Western Blot at 1:2000 dilution Lane 1: NCI-H460 whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 ug per lane.
Western Blot at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: SW480 whole cell lysate Lysates/proteins at 20 ug per lane.
Western Blot at 1:2000 dilution Lane 1: Hela whole cell lysates Lane 2: PC-3 whole cell lysates Lane 3: SW480 whole cell lysates Lysates/proteins at 20 ug per lane.
Western Blot at 1:1000 dilution + NCI-H460 whole cell lysates Lysates/proteins at 20 ug per lane.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

Documents

Further Information

Additional Names:
Solute carrier organic anion transporter family member 1B3, Liver-specific organic anion transporter 2, LST-2, Organic anion transporter 8, Organic anion-transporting polypeptide 8, OATP-8, Solute carrier family 21 member 8, SLCO1B3, LST2, OATP1B3, OATP8,SLC21A8
Application Note:
For WB starting dilution is: 1:2000
Background:
SLCO1B3 belongs to the organic anion transporter (OATP) family. OATPs are involved in the membrane transport of bile acids, conjugated steroids, thyroid hormone, eicosanoids, peptides, and numerous drugs in many tissues (Mikkaichi et al., 2004 [PubMed 14993604]).
Background References:
  • Hu, M., et al. Pharmacogenet. Genomics 20(10):634-637(2010)
  • Weiner, M., et al. Antimicrob. Agents Chemother. 54(10):4192-4200(2010)
  • Kang, T.W., et al. Hum. Mol. Genet. 19(18):3672-3678(2010)
  • Takahashi, N., et al. J. Hum. Genet. (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SLCO1B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 639-668 amino acids from the C-terminal region of human SLCO1B3.
NCBI Gene ID #:
28234
NCBI Official Name:
Solute carrier organic anion transporter family member 1B3
NCBI Official Symbol:
SLCO1B3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
77 kDa
Protein Accession #:
Q9NPD5
Protein GI Number:
27734563
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9NPD5
User NOte:
Optimal dilutions for each application to be determined by the researcher.