POLS Antibody

ProSci
Product Code: PSI-58-801
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-801-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).

Western blot analysis in SK-BR-3 cell line lysates (35ug/lane).

Further Information

Additional Names:
Non-canonical poly(A) RNA polymerase PAPD7, DNA polymerase sigma, LAK-1, PAP-associated domain-containing protein 7, TRAMP-like complex polyadenylate polymerase, Terminal uridylyltransferase 5, TUTase 5, Topoisomerase-related function protein 4-1, TRF4-1, PAPD7, POLS, TRF4
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a DNA polymerase that is likely involved in DNA repair. In addition, the encoded protein may be required for sister chromatid adhesion. Alternatively spliced transcript variants that encode different isoforms have been described.
Background References:
  • Jarjanazi, H., et al. Hum. Mutat. 29(4):461-467(2008)
  • Carson, D.R., et al. Proc. Natl. Acad. Sci. U.S.A. 98(15):8270-8275(2001)
  • Wang, Z., et al. Science 289(5480):774-779(2000)
  • Walowsky, C., et al. J. Biol. Chem. 274(11):7302-7308(1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This POLS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the Central region of human POLS.
NCBI Gene ID #:
11044
NCBI Official Name:
Non-canonical poly(A) RNA polymerase PAPD7
NCBI Official Symbol:
PAPD7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
82 kDa
Protein Accession #:
Q5XG87
Protein GI Number:
60392922
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q5XG87
User NOte:
Optimal dilutions for each application to be determined by the researcher.