WHSC1 Antibody
| Code | Size | Price |
|---|
| PSI-58-927-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Histone-lysine N-methyltransferase NSD2, Multiple myeloma SET domain-containing protein, MMSET, Nuclear SET domain-containing protein 2, NSD2, Protein trithorax-5, Wolf-Hirschhorn syndrome candidate 1 protein, WHSC1, WHSC1, KIAA1090, MMSET, NSD2, TRX5
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that contains four domains
present in other developmental proteins: a PWWP domain, an HMG box,
a SET domain, and a PHD-type zinc finger. It is expressed
ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS)
is a malformation syndrome associated with a hemizygous deletion of
the distal short arm of chromosome 4. This gene maps to the 165 kb
WHS critical region and has also been involved in the chromosomal
translocation t(4;14)(p16.3;q32.3) in multiple myelomas.
Alternative splicing of this gene results in multiple transcript
variants encoding different isoforms. Some transcript variants are
nonsense-mediated mRNA (NMD) decay candidates, hence not
represented as reference sequences.
Background References:
- Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
- Kang, H.B., et al. FEBS Lett. 583(12):1880-1886(2009)
- Kassambara, A., et al. Biochem. Biophys. Res. Commun. 379(4):840-845(2009)
- Brito, J.L., et al. Haematologica 94(1):78-86(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This WHSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1061-1089 amino acids from the C-terminal region of human WHSC1.
NCBI Gene ID #:
7468
NCBI Official Name:
Histone-lysine N-methyltransferase NSD2
NCBI Official Symbol:
WHSC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
152 kDa
Protein Accession #:
O96028
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O96028
User NOte:
Optimal dilutions for each application to be determined by the researcher.