DMRT1 Antibody

ProSci
Product Code: PSI-60-338
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-338-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 1
Western blot analysis in MCF-7 cell line lysates (35ug/lane).

Western blot analysis in MCF-7 cell line lysates (35ug/lane).

Further Information

Additional Names:
Doublesex- and mab-3-related transcription factor 1, DM domain expressed in testis protein 1, DMRT1, DMT1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.
Background References:
  • Kang, J.U., et al. Int. J. Oncol. 37(2):327-335(2010)
  • Turnbull, C., et al. Nat. Genet. 42(7):604-607(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Krentz, A.D., et al. Proc. Natl. Acad. Sci. U.S.A. 106(52):22323-22328(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DMRT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-322 amino acids from the C-terminal region of human DMRT1.
NCBI Gene ID #:
1761
NCBI Official Name:
Doublesex- and mab-3-related transcription factor 1
NCBI Official Symbol:
DMRT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
Q9Y5R6
Protein GI Number:
83305820
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9Y5R6
User NOte:
Optimal dilutions for each application to be determined by the researcher.