GEMIN4 Antibody
Code | Size | Price |
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PSI-60-915-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Gem-associated protein 4, Gemin-4, Component of gems 4, p97, GEMIN4
Application Note:
For WB starting dilution is: 1:1000
Background:
The product of this gene is part of a large complex
localized to the cytoplasm, nucleoli, and to discrete nuclear
bodies called Gemini bodies (gems). The complex functions in
spliceosomal snRNP assembly in the cytoplasm, and regenerates
spliceosomes required for pre-mRNA splicing in the nucleus. The
encoded protein directly interacts with a DEAD box protein and
several spliceosome core proteins. Alternatively spliced transcript
variants have been described, but their biological validity has not
been determined.
Background References:
- Kim, J.S., et al. Mol. Carcinog. 49(10):913-921(2010)
- Wilker, E.H., et al. Environ. Health Perspect. 118(7):943-948(2010)
- Boni, V., et al. Pharmacogenomics J. (2010) In press :
- Clague, J., et al. Mol. Carcinog. 49(2):183-189(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GEMIN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-301 amino acids from the N-terminal region of human GEMIN4.
NCBI Gene ID #:
50628
NCBI Official Name:
Gem-associated protein 4
NCBI Official Symbol:
GEMIN4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
120 kDa
Protein Accession #:
P57678
Protein GI Number:
322510030
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P57678
User NOte:
Optimal dilutions for each application to be determined by the researcher.