CENPE Antibody
| Code | Size | Price |
|---|
| PSI-59-572-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Centromere-associated protein E, Centromere protein E, CENP-E, Kinesin-related protein CENPE, CENPE
Application Note:
For WB starting dilution is: 1:1000
Background:
Centrosome-associated protein E is a kinesin-like motor
protein that accumulates in the G2 phase of the cell cycle. Unlike
other centrosome-associated proteins, it is not present during
interphase and first appears at the centromere region of
chromosomes during prometaphase. CENPE is proposed to be one of the
motors responsible for mammalian chromosome movement and/or spindle
elongation.
Background References:
- Kim, Y., et al. Cell 142(3):444-455(2010)
- Maia, A.F., et al. Chromosoma 119(4):405-413(2010)
- Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
- Maffini, S., et al. Curr. Biol. 19(18):1566-1572(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CENPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2573-2601 amino acids from the C-terminal region of human CENPE.
NCBI Gene ID #:
1062
NCBI Official Name:
Centromere-associated protein E
NCBI Official Symbol:
CENPE
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
316 kDa
Protein Accession #:
Q02224
Protein GI Number:
160358869
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q02224
User NOte:
Optimal dilutions for each application to be determined by the researcher.