EIF4A3 Antibody
| Code | Size | Price |
|---|
| PSI-60-471-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Eukaryotic initiation factor 4A-III, eIF-4A-III, eIF4A-III, ATP-dependent RNA helicase DDX48, ATP-dependent RNA helicase eIF4A-3, DEAD box protein 48, Eukaryotic initiation factor 4A-like NUK-34, Eukaryotic translation initiation factor 4A isoform 3, Nuclear matrix protein 265, NMP 265, hNMP 265, Eukaryotic initiation factor 4A-III, N-terminally processed, EIF4A3, DDX48, KIAA0111
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the DEAD box protein family.
DEAD box proteins, characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration
of RNA secondary structure, such as translation initiation, nuclear
and mitochondrial splicing, and ribosome and spliceosome assembly.
Based on their distribution patterns, some members of this family
are believed to be involved in embryogenesis, spermatogenesis, and
cellular growth and division. The protein encoded by this gene is a
nuclear matrix protein. Its amino acid sequence is highly similar
to the amino acid sequences of the translation initiation factors
eIF4AI and eIF4AII, two other members of the DEAD box protein
family.
Background References:
- Koroleva, O.A., et al. Plant Cell 21(5):1592-1606(2009)
- Karam, R., et al. Oncogene 27(30):4255-4260(2008)
- Ma, X.M., et al. Cell 133(2):303-313(2008)
- Giorgi, C., et al. Cell 130(1):179-191(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Xenopus, Bovine, Chicken, Zebrafish, Monkey, Mouse, Pig, Rat
Immunogen:
This EIF4A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-325 amino acids from the C-terminal region of human EIF4A3.
NCBI Gene ID #:
9775
NCBI Official Name:
Eukaryotic initiation factor 4A-III
NCBI Official Symbol:
EIF4A3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
P38919
Protein GI Number:
20532400
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
P38919
User NOte:
Optimal dilutions for each application to be determined by the researcher.