CPSF6 Antibody

ProSci
Product Code: PSI-60-961
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-961-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 ug per lane.
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Western blot analysis in Hela cell line lysates (35ug/lane).

Western Blot at 1:1000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 ug per lane.
Western blot analysis in Hela cell line lysates (35ug/lane).

Further Information

Additional Names:
Cleavage and polyadenylation specificity factor subunit 6, Cleavage and polyadenylation specificity factor 68 kDa subunit, CFIm68, CPSF 68 kDa subunit, Pre-mRNA cleavage factor Im 68 kDa subunit, Protein HPBRII-4/7, CPSF6, CFIM68
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.
Background References:
  • Lee, K., et al. Cell Host Microbe 7(3):221-233(2010)
  • Ruepp, M.D., et al. Mol. Biol. Cell 20(24):5211-5223(2009)
  • Xin, X., et al. Genome Res. 19(7):1262-1269(2009)
  • Maggi, L.B. Jr., et al. Mol. Cell. Biol. 28(23):7050-7065(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Zebrafish, Mouse, Xenopus
Immunogen:
This CPSF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-51 amino acids from the N-terminal region of human CPSF6.
NCBI Gene ID #:
11052
NCBI Official Name:
Cleavage and polyadenylation specificity factor subunit 6
NCBI Official Symbol:
CPSF6
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
59 kDa
Protein Accession #:
Q16630
Protein GI Number:
88909266
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q16630
User NOte:
Optimal dilutions for each application to be determined by the researcher.