XRN2 Antibody
| Code | Size | Price |
|---|
| PSI-57-673-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
5'-3' exoribonuclease 2, 3113-, DHM1-like protein, DHP protein, XRN2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene shares similarity with the mouse Dhm1 and the
yeast dhp1 gene. The yeast gene is involved in homologous
recombination and RNA metabolism, such as RNA synthesis and RNA
trafficking. Complementation studies show that Dhm1 has a similar
function in mouse as dhp1. The function of the human gene has not
yet been determined. Transcript variants encoding different
isoforms have been noted for this gene; however, their full-length
nature is not known.
Background References:
- Lu, Y., et al. Oncogene 29(7):1041-1049(2010)
- Yang, X.C., et al. Mol. Cell. Biol. 29(1):31-42(2009)
- Kaneko, S., et al. Genes Dev. 21(14):1779-1789(2007)
- Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Drosophila, Mouse
Immunogen:
This XRN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-76 amino acids from the N-terminal region of human XRN2.
NCBI Gene ID #:
22803
NCBI Official Name:
5'-3' exoribonuclease 2
NCBI Official Symbol:
XRN2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
109 kDa
Protein Accession #:
Q9H0D6
Protein GI Number:
30173484
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9H0D6
User NOte:
Optimal dilutions for each application to be determined by the researcher.