NHEJ1 Antibody
| Code | Size | Price |
|---|
| PSI-57-772-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Non-homologous end-joining factor 1, Protein cernunnos, XRCC4-like factor, NHEJ1, XLF
Application Note:
For WB starting dilution is: 1:1000
Background:
Double-strand breaks in DNA result from genotoxic stresses
and are among the most damaging of DNA lesions. This gene encodes a
DNA repair factor essential for the nonhomologous end-joining
pathway, which preferentially mediates repair of double-stranded
breaks. Mutations in this gene cause different kinds of severe
combined immunodeficiency disorders.
Background References:
- Malivert, L., et al. J. Biol. Chem. 285(34):26475-26483(2010)
- Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010)
- Okada, Y., et al. Hum. Mol. Genet. 19(11):2303-2312(2010)
- Andres, S.N., et al. Mol. Cell 28(6):1093-1101(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NHEJ1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-296 amino acids from the C-terminal region of human NHEJ1.
NCBI Gene ID #:
79840
NCBI Official Name:
Non-homologous end-joining factor 1
NCBI Official Symbol:
NHEJ1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
Q9H9Q4
Protein GI Number:
74734059
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q9H9Q4
User NOte:
Optimal dilutions for each application to be determined by the researcher.