FUSIP1 Antibody
| Code | Size | Price |
|---|
| PSI-59-189-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Serine/arginine-rich splicing factor 10, 40 kDa SR-repressor protein, SRrp40, FUS-interacting serine-arginine-rich protein 1, Splicing factor SRp38, Splicing factor, arginine/serine-rich 13A, TLS-associated protein with Ser-Arg repeats, TASR, TLS-associated protein with SR repeats, TLS-associated serine-arginine protein, TLS-associated SR protein, SRSF10, FUSIP1, FUSIP2, SFRS13A, TASR
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene product is a member of the serine-arginine (SR)
family of proteins, which is involved in constitutive and regulated
RNA splicing. Members of this family are characterized by
N-terminal RNP1 and RNP2 motifs, which are required for binding to
RNA, and multiple C-terminal SR/RS repeats, which are important in
mediating association with other cellular proteins. This protein
can influence splice site selection of adenovirus E1A pre-mRNA. It
interacts with the oncoprotein TLS, and abrogates the influence of
TLS on E1A pre-mRNA splicing. This gene has multiple pseudogenes.
Alternative splicing of this gene results in multiple transcript
variants encoding different isoforms. In addition, transcript
variants utilizing alternative polyA sites exist.
Background References:
- Manley, J.L., et al. Genes Dev. 24(11):1073-1074(2010)
- Ling, I.F., et al. Hum. Mutat. 31(6):702-709(2010)
- Shi, Y., et al. Mol. Cell 28(1):79-90(2007)
- Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This FUSIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-225 amino acids from the C-terminal region of human FUSIP1.
NCBI Gene ID #:
10772
NCBI Official Name:
Serine/arginine-rich splicing factor 10
NCBI Official Symbol:
SRSF10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
31 kDa
Protein Accession #:
O75494
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O75494
User NOte:
Optimal dilutions for each application to be determined by the researcher.