POLR2D Antibody
Code | Size | Price |
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PSI-59-030-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
DNA-directed RNA polymerase II subunit RPB4, RNA polymerase II subunit B4, DNA-directed RNA polymerase II subunit D, RNA polymerase II 16 kDa subunit, RPB16, POLR2D
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes the fourth largest subunit of RNA
polymerase II, the polymerase responsible for synthesizing
messenger RNA in eukaryotes. In yeast, this polymerase subunit is
associated with the polymerase under suboptimal growth conditions
and may have a stress protective role. A sequence for a ribosomal
pseudogene is contained within the 3' untranslated region of the
transcript from this gene.
Background References:
- Michiels, S., et al. Carcinogenesis 30(5):763-768(2009)
- Meka, H., et al. Nucleic Acids Res. 33(19):6435-6444(2005)
- Zhou, M., et al. Proc. Natl. Acad. Sci. U.S.A. 100(22):12666-12671(2003)
- Kaehlcke, K., et al. Mol. Cell 12(1):167-176(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This POLR2D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the Central region of human POLR2D.
NCBI Gene ID #:
5433
NCBI Official Name:
DNA-directed RNA polymerase II subunit RPB4
NCBI Official Symbol:
POLR2D
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
16 kDa
Protein Accession #:
O15514
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
O15514
User NOte:
Optimal dilutions for each application to be determined by the researcher.