INTS1 Antibody

ProSci
Product Code: PSI-56-305
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-305-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in human placenta tissue lysates (35ug/lane).

Western blot analysis in human placenta tissue lysates (35ug/lane).

Further Information

Additional Names:
Integrator complex subunit 1, Int1, INTS1, KIAA1440
Application Note:
For WB starting dilution is: 1:1000
Background:
INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).
Background References:
  • Nusbaum, C., et al. Nature 439(7074):331-335(2006)
  • Baillat, D., et al. Cell 123(2):265-276(2005)
  • Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This INTS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 113-142 amino acids from the N-terminal region of human INTS1.
NCBI Gene ID #:
26173
NCBI Official Name:
Integrator complex subunit 1
NCBI Official Symbol:
INTS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
244 kDa
Protein Accession #:
Q8N201
Protein GI Number:
97052424
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Swissprot #:
Q8N201
User NOte:
Optimal dilutions for each application to be determined by the researcher.